Cellular therapy reverses myocardial dysfunction
نویسندگان
چکیده
منابع مشابه
S100A1 genetically targeted therapy reverses dysfunction of human failing cardiomyocytes.
OBJECTIVES This study investigated the hypothesis whether S100A1 gene therapy can improve pathological key features in human failing ventricular cardiomyocytes (HFCMs). BACKGROUND Depletion of the Ca²⁺-sensor protein S100A1 drives deterioration of cardiac performance toward heart failure (HF) in experimental animal models. Targeted repair of this molecular defect by cardiac-specific S100A1 ge...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2001
ISSN: 0022-5223
DOI: 10.1067/mtc.2001.112937